Methods and compositions for stabilizing the myocardium
US9415135B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 29, 2012 |
| Grant date | Aug 16, 2016 |
| Priority date | — |
| Expiry date | Dec 24, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides materials and methods that can serve as a prosthetic and/or, for tissue engineer applications, as a supporting matrix in the stabilization of the myocardium. For example, the present invention provides methods of stabilizing an injured or defective myocardial wall in a patient including forming a prosthetic in situ by injecting, at a pre-selected site in the myocardial wall of the patient, a polymer network including: a cross-linked polymer, the cross-linked polymer being a hydrogel; and a linear polymer, the polymer chains of which are entangled within the cross-linked polymer, wherein the linear polymer is not covalently bonded to the cross-linked polymer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.