Eluting medical devices

US9415193B2 · kind B2 · utility

Assignee

• W.L. Gore & Associates GmbH · DE

Inventors

• Carey V. Campbell · Flagstaff, US
• Robert L. Cleek · Flagstaff, US
• Daniel L. Crandall · Flagstaff, US
• James F. Davidson · Flagstaff, US
• Paul D. Drumheller · Flagstaff, US
• Cody L. Hartman · Flagstaff, US
• Theresa A. Holland · Flagstaff, US
• Thane L. Kranzler · Flagstaff, US
• Mei Li · Flagstaff, US
• Gregory LoStracco · Tucson, US
• Bruce M. Steinhaus · Parker, US
• Benjamin M. Trapp · Flagstaff, US
• Thomas G. Triebes · Flagstaff, US

Key dates

• Filing date: Sep 4, 2012
• Grant date: Aug 16, 2016
• Expiry date: Sep 4, 2032

Classification

• Technology area (CPC F): Mechanical Engineering; Lighting; Heating
• CPC primary: F04C2270/0421
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

The invention is directed to eluting medical devices that enable consistent “on-demand” delivery of therapeutic agents to a vessel. The medical device of the current invention comprises an expandable member, a hydrophilic coating comprising at least one therapeutic agent about the expandable member or structural layer and an outer sheath with a variably permeable microstructure. The design and methods disclosed herein ensures that therapeutic agent delivery occurs essentially only during expansion of the expandable member, minimizing coating and/or therapeutic agent loss to the bloodstream and providing controlled delivery to the treatment site.