Patent · US Active

Stable liquid formulations of dimer VEGF antagonists

US9416167B2 · kind B2 · utility

48Cited by

14References

8Claims

0Family size

Assignee

REGENERON PHARMACEUTICALS, INC. · US

Inventors

Daniel Dix · Lagrangeville, US
Kelly Frye · Mendham, US
Susan KAUTZ · Albany, US

Key dates

Filing date	Nov 21, 2014
Grant date	Aug 16, 2016
Priority date	—
Expiry date	Nov 21, 2034

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Formulations of a vascular endothelial growth factor (VEGF)-specific fusion protein antagonist are provided including a pre-lyophilized formulation, a reconstituted lyophilized formulation, and a stable liquid formulation. Preferably, the fusion protein has the sequence of SEQ ID NO:4.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.