Patent · US Active

Combination product comprising phentermine and topiramate, and preparation method thereof

US9421188B2 · kind B2 · utility

0Cited by

1References

25Claims

0Family size

Assignee

INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY, ACADEMY OF MILITARY MEDICAL SCIENCES · CN

Inventors

Song Li · Beijing, CN
Chunsheng Gao · Beijing, CN
Wu Zhong · Beijing, CN
Yuli Wang · Tianjin, CN
Meiyan Yang · Beijing, CN
Li Shan · Beijing, CN
Xinbo Zhou · Beijing, CN
Zhibing Zheng · Beijing, CN
Xiaokui Wang · Beijing, CN

Key dates

Filing date	Mar 20, 2013
Grant date	Aug 23, 2016
Priority date	—
Expiry date	Mar 20, 2033

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P25/18
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a combination product, which comprises immediate release pellet of phentermine and sustained-release pellet of topiramate, wherein the pellet of topiramate includes: a) a blank pellet core; b) an active drug layer that contains topiramate and is free of binding agent, the layer being located on surface of the blank pellet core; c) a sustained-release coating layer containing ethyl cellulose and PVP K30, the sustained-release coating layer being located on external of the active drug layer. The present invention further discloses a method for preparing the combination product.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.