Methods for modulating Th1/Th2 cell balance by increasing leptin activity
US9421257B2 · kind B2 · utility
3Cited by
5References
14Claims
0Family size
Inventors
Key dates
| Filing date | Jan 16, 2015 |
| Grant date | Aug 23, 2016 |
| Priority date | — |
| Expiry date | Jan 16, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to methods for modulating the Th/Th2 cell balance toward anti-inflammatory cytokine producing cells in a subject comprising decreasing the amount, the expression, or the activity of leptin in a subject sufficient to modulate the Th1/Th2 cell balance toward anti-inflammatory cytokine producing cells. The invention is also directed to methods of treatment of an immune-related disorder in a subject comprising decreasing the amount, the expression, or the activity of leptin in the subject sufficient to treat the immune-related disorder.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.