Patent · US Active

Antibodies that bind OV064 and methods of use therefor

US9421277B2 · kind B2 · utility

4Cited by
13References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 9, 2014
Grant dateAug 23, 2016
Priority date—
Expiry dateAug 20, 2034

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/705
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Antibodies and antigen-binding fragments of antibodies that bind OV064 are disclosed. The antibodies bind an extracellular domain of OV064. Some of the antibodies and antigen-binding fragments bind an epitope on OV064 sufficient to induce internalization. In some embodiments, the antibodies are humanized, chimeric or human. Nucleic acids and vectors encoding the antibodies or portions thereof, recombinant cells that contain the nucleic acids, and compositions comprising the antibodies or antigen-binding fragments are also disclosed. The invention also provides therapeutic and diagnostic methods utilizing the antibodies and antigen-binding fragments provided herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.