Target vector with activable imaging function

US9421281B2 · kind B2 · utility

Assignees

• CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE · FR
• COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES · FR
• Institut National de la Sante et de la Recherche Medicale (INSERM) · FR
• The Joseph Fourier University of Grenoble · FR

Inventors

• Isabelle Texier-Nogues · Grenoble, FR
• Jean-Luc Coll · Le Pont-de-Claix, FR
• Pascal Dumy · Grenoble, FR
• Didier Boturyn · Grenoble, FR
• Marie Favrot · Meylan, FR

Key dates

• Filing date: Jul 18, 2006
• Grant date: Aug 23, 2016
• Expiry date: Apr 3, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention concerns the field of molecular probe architecture for in vivo imaging. More particularly, the invention concerns molecular constructs providing an imaging function activable in intracellular environment. The inventive fluorescence probes enable in particular images of certain targeted tissues to be formed, while maintaining a low background noise level and, preferably, while obtaining at the targeted tissue, an imaging signal increasing in time.