Bisulfate of janus kinase (JAK) inhibitor and preparation method therefor
US9422300B2 · kind B2 · utility
6Cited by
1References
9Claims
0Family size
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Key dates
| Filing date | May 5, 2014 |
| Grant date | Aug 23, 2016 |
| Priority date | — |
| Expiry date | May 5, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a bisulfate of a Janus kinase (JAK) inhibitor and a preparation method therefor. More specifically, the present invention relates to a (3aR,5s,6aS)—N-(3-methoxyl-1,2,4-thiadiazole-5-group)-5-(methyl(7H-pyrrolo[2,3-d]pyrimidine-4-group)amino)hexahydrocyclopenta[c]pyrrole-2(1H)-formamide bisulfate shown in the formula (I), a preparation method therefor, and an application thereof. The bisulfate shown in the formula (I) can be well suitable as a Janus kinase (JAK) inhibitor in clinical work for treating rheumatism or rheumatoid arthritis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.