Patent · US Active

Modified alginates for cell encapsulation and cell therapy

US9422373B2 · kind B2 · utility

6Cited by

6References

37Claims

0Family size

Assignee

Massachusetts Institute of Technology · US

Inventors

Arturo Jose Vegas · Belmont, US
Minglin Ma · Ithaca, US
Kaitlin M. Bratlie · Ames, US
Daniel Griffith Anderson · Framingham, US
Robert S. Langer · Newton, US

Key dates

Filing date	Jun 4, 2012
Grant date	Aug 23, 2016
Priority date	—
Expiry date	Jul 3, 2032

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K9/5161
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for the encapsulation and transplantation of cells. Also disclosed are high throughput methods for the characterizing the biocompatibility and physiochemical properties of modified alginate polymers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.