Gene cluster for biosynthesis of griselimycin and methylgriselimycin

US9422566B2 · kind B2 · utility

Assignee

• Sanofi · FR

Inventors

• Mark Broenstrup · Frankfurt am Main, DE
• Claudia Koenig · Frankfurt, DE
• Luigi Toti · Hochheim, DE
• Joachim Wink · Rödermark, DE
• Wulf-Dirk Leuschner · Frankfurt am Main, DE
• Johann Gassenhuber · Wiesbaden, DE
• Rolf Muller · Marburg, DE
• Silke Wenzel · Riegelsberg, DE
• Tina Binz · Bellinzona, CH
• Carsten Volz · Saarburg, DE

Key dates

• Filing date: Oct 11, 2012
• Grant date: Aug 23, 2016
• Expiry date: Oct 11, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12R2001/465
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention refers to the gene cluster and genes comprised by the gene cluster which are involved in the biosynthesis of griselimycin and methylgriselimycin and to the use of the gene cluster, genes comprised thereby and proteins encoded thereby for the production of antibiotic agents.