Multi-phased, biodegradable and oesteointegrative composite scaffold for biological fixation of musculoskeletal soft tissue to bone

US9427495B2 · kind B2 · utility

Assignee

• The Trustees of Columbia University in the City of New York · US

Inventors

• Helen H. Lu · New York, US
• Jeffrey Spalazzi · Staten Island, US
• Kathie Kionisio · Andover, US

Key dates

• Filing date: Aug 4, 2014
• Grant date: Aug 30, 2016
• Expiry date: Aug 4, 2034

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2430/34
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Methods and apparatuses are provided for musculoskeletal tissue engineering. For example, a scaffold apparatus is provided which comprises microspheres of selected sizes and/or composition. The microspheres are layered to have a gradient of microsphere sizes and/or compositions. The scaffold provides a functional interface between multiple tissue types.