N-[4-(quinolin-4-yloxy)cyclohexyl(methyl)](hetero)arylcarboxamides as androgen receptor antagonists, production and use thereof as medicinal products

US9428460B2 · kind B2 · utility

Assignee

• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Duy Nguyen · Berlin, DE
• Hermann Kunzer · Hermeskeil, DE
• Hortensia Faus Gimenez · Berlin, DE
• Benjamin Bader · Berlin, DE
• Silke Köhr · Teltow, DE
• Martin Fritsch · Berlin, DE

Key dates

• Filing date: Jun 24, 2013
• Grant date: Aug 30, 2016
• Expiry date: Jun 24, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to N-[4-(quinolin-4-yloxy)cyclohexyl(methyl)](hetero)arylcarboxamides, intermediates and methods for their production, use thereof for treating and/or preventing diseases and use thereof for producing medicinal products and use thereof for treating and/or preventing diseases, especially of hyperproliferative diseases.