Nuclear transport modulators and uses thereof
US9428490B2 · kind B2 · utility
23Cited by
6References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 26, 2012 |
| Grant date | Aug 30, 2016 |
| Priority date | — |
| Expiry date | Jul 26, 2032 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02E10/549
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention generally relates to nuclear transport modulators, e.g CRM1 inhibitors, and more particularly to a compound represented by formula (I): or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula (I), or a pharmaceutically acceptable salt or composition thereof, e.g, in the treatment, modulation and/or prevention of physiological conditions associated with CRM1 activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.