Patent · US Active

Substituted azoles, antiviral active component, pharmaceutical composition, method for preparation and use thereof

US9428491B2 · kind B2 · utility

0Cited by

3References

3Claims

0Family size

Inventors

Alexandre Vasilievich Ivachtchenko · Encinitas, US
Vadim Bichko · San Diego, US
Oleg Dmitrievich Mitkin · Moskovskiy, RU

Key dates

Filing date	Nov 28, 2011
Grant date	Aug 30, 2016
Priority date	—
Expiry date	Nov 28, 2031

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to novel antiviral active 5-{4-[1H-imidazol-5-ylaryl(or hetaryl)]-buta-1,3-diynyl}-1H-imidazoles of the general formula 1 and pharmaceutically acceptable salt thereof, pharmaceutical composition, antiviral medicament, therapeutic kit for prophylaxis and treatment of hepatisis C virus diseases, and method for prophylaxis and treatment of hepatisis C.wherein:R1 and R2—represent optionally identical radicals selected from 2.1 and 2.2, where an asterisk (*) denotes the position of attachment to the imidazole fragment, (S) and (R) are types of chiral centers;R3 is isopropyl or phenyl radicals;Ar an aromatic or heteroaromatic diradical.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.