Tandem purification of proteins
US9428546B2 · kind B2 · utility
2Cited by
0References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 29, 2011 |
| Grant date | Aug 30, 2016 |
| Priority date | — |
| Expiry date | Jan 5, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K16/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure provides methods for purifying products from a fluid. In some embodiments, provided purification methods use a combination of purification modes (e.g., protein A and ion exchange) operated in tandem, wherein at least one of the modes utilizes weak partitioning. In some embodiments, provided purification methods operate under robust conditions in which a degree of binding between a product and resin is maintained despite variations in operating parameters.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.