Compositions and methods for capture and elution of biological materials via particulates
US9428725B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 14, 2014 |
| Grant date | Aug 30, 2016 |
| Priority date | — |
| Expiry date | Apr 13, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2001/4088
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A flow-through device for capturing a biological material from a fluid specimen and lysing the fluid specimen. The flow through device may include a first chamber containing a portion of the fluid specimen and a solid phase material retained in the first chamber. The solid phase material may have an affinity for the biological material in the fluid specimen. The first chamber may include an inlet opening which allows flow of the fluid specimen into the first chamber. The first chamber may also include an outlet opening which allows flow of the fluid specimen out of the first chamber. The flow through device may include a second chamber fluidly connected to the first chamber. The second chamber may include a portion of the fluid specimen and an impeller. The impeller may in use impart rotational motion to the fluid specimen to mechanically lyse the fluid specimen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.