Patent · US Active

Cell culture medium

US9428727B2 · kind B2 · utility

2Cited by

8References

12Claims

0Family size

Assignee

Novartis AG · CH

Inventors

Christian Leist · Basel, CH
Petra Meissner · Jülich, DE
Jörg Schmidt · Schneeberg, DE

Key dates

Filing date	Apr 25, 2011
Grant date	Aug 30, 2016
Priority date	—
Expiry date	Apr 25, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2500/12
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present application describes an optimized medium for growth of mammalian cells as well as polypeptide production. The cell culture medium is characterized by a Sow ratio of sodium to potassium ions, it further relates to the method of producing polypeptides using such cell culture media. Sn another aspect, the method of polypeptide production can also comprise a temperature shift and/or a pH-shift to further optimize growth and product yield.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.