Patent · US Active

Sample transferring apparatus for mass cytometry

US9431227B2 · kind B2 · utility

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9References
10Claims
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Inventor

Key dates

Filing dateJan 12, 2015
Grant dateAug 30, 2016
Priority date
Expiry dateJan 12, 2035

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2015/1006
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

In a mass cytometer or mass spectrometer, a sample of elemental tagged particles is transferred from a dispersion to a gas flow through a carrier aerosol spray for atomization and ionization by inductively coupled plasma (ICP) source. The configuration of the sample transfer apparatus allow for total consumption of the sample by passing the sample spray through a deceleration stage to decelerate the spray of particles from its high velocity expansion. Following the deceleration stage, the decelerated sample of particles can be accelerated and focused through an acceleration stage for transferring into the ICP. This effectively improves the particle transfer between the sample spray and the ICP.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.