Process for producing optically active succinimide derivatives and intermediates thereof
US9434737B2 · kind B2 · utility
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Key dates
| Filing date | Dec 12, 2013 |
| Grant date | Sep 6, 2016 |
| Priority date | — |
| Expiry date | Jan 23, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/07
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided is a process for producing (3R)-2′-(4-bromo-2-fluorobenzyl)spiro{pyrrolidine-3,4′(1′H)-pyrrolo[1,2-a]pyrazine}-1′,2,3′,5(2′H)-tetraone (compound A). The method includes converting an optically active succinimide derivative of formula (I) to compound A, in which the compound of formula (I) has been prepared by reacting a base with an optically active amide derivative of formula (VI).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.