Indazole derivatives

US9434743B2 · kind B2 · utility

Assignee

• Takeda Pharmaceutical Company Limited · JP

Inventors

• Zacharia Cheruvallath · San Diego, US
• Philip Erickson · San Diego, US
• Jun Feng · San Diego, US
• Mallareddy Komandla · San Diego, US
• John David Lawson · San Diego, US
• Christopher McBride · Oakland, US
• Joanne Miura · San Diego, US
• Sean Murphy · San Diego, US
• Mingnam Tang · San Diego, US
• Huong-Thu Ton-Nu · San Diego, US

Key dates

• Filing date: Feb 28, 2013
• Grant date: Sep 6, 2016
• Expiry date: May 9, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are compounds of Formula 1,and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, and R6 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating obesity and related diseases, disorders, and conditions associated with MetAP2.