Systems and methods for enhanced SCODA
US9434938B2 · kind B2 · utility
3Cited by
39References
18Claims
0Family size
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Key dates
| Filing date | Aug 16, 2013 |
| Grant date | Sep 6, 2016 |
| Priority date | — |
| Expiry date | Jan 3, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/385
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods and apparatus for separating, concentrating and/or detecting molecules based on differences in binding affinity to a probe are provided. The molecules may be differentially modified. The molecules may be differentially methylated nucleic acids. The methods can be used in fields such as epigenetics or oncology to selectively concentrate or detect the presence of specific biomolecules or differentially modified biomolecules, to provide diagnostics for disorders such as fetal genetic disorders, to detect biomarkers in cancer, organ failure, disease states, infection or the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.