Enhanced deposition of chromogens utilizing pyrimidine analogs
US9435795B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 6, 2014 |
| Grant date | Sep 6, 2016 |
| Priority date | — |
| Expiry date | Oct 6, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/581
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This disclosure relates to compositions that enhance the deposition of detectable moieties on tissue samples, methods utilizing these compositions and kits including these compositions. The compositions include a deposition enhancer having a formulawhere R1, R2, R3, and R4 are independently selected from aliphatic, aryl, halogen, a heteroatom-containing moiety, and hydrogen; R1 and/or R3 can be bound to R2 to form a fused, aromatic ring system; R5 is selected from a heteroatom-containing moiety; A is selected from, a carbon atom, a heteroatom, other than sulfur, and any combination thereof; n is 1-5, an enzyme, a specific binding moiety and a detectable moiety.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.