Method for producing 4-haloalkyl-3-mercapto-substituted 2-hydroxy-benzoic acid derivatives

US9440917B2 · kind B2 · utility

Assignee

• BAYER CROPSCIENCE AKTIENGESELLSCHAFT · DE

Inventors

• Mark James Ford · Nordenstadt, DE
• Gunter Karig

Key dates

• Filing date: Dec 10, 2013
• Grant date: Sep 13, 2016
• Expiry date: Dec 10, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C323/54
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process is described for preparing 4-haloalkyl-3-mercapto-substituted 2-hydroxybenzoic acid derivatives of the general formula (I) by reaction of 4-thio-substituted β-keto esters of the formula (II) with alkoxyvinyl haloalkyl ketones of the formula (III) in the presence of a base.In the above formulae, X, R1, R2 and R3 are each hydrogen, halogen, alkyl, alkoxy and cycloalkyl.