Patent · US Active

Difluorolactam compositions for EP4-mediated osteo related diseases and conditions

US9440919B2 · kind B2 · utility

4Cited by

15References

23Claims

0Family size

Assignees

CAYMAN CHEMICAL COMPANY, INC. · US
MYOMETRICS LLC · US

Inventors

Stephen Douglas Barrett · Hartland, US
Fred Lawrence Ciske · Dexter, US
Joseph Michael Colombo · Ann Arbor, US
Gregory William Endres · Saline, US
Bradlee David Germain · Ann Arbor, US
Andriy Kornilov · Ypsilanti, US
James Bernard Kramer · Sylvania, US
Adam Uzieblo · Farmington Hills, US
Thomas Allen Owen · Pequannock, US
James Paul O'Malley · Dunedin, NZ

Key dates

Filing date	Jul 19, 2013
Grant date	Sep 13, 2016
Priority date	—
Expiry date	Jul 19, 2033

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61L2430/02
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed herein are compositions and methods of treating osteoporosis, bone fracture, bone loss, and increasing bone density by administration of compounds of formula (I)or compositions comprising a compound of formula (I) and a pharmaceutically acceptable carrier, wherein L1, L2, L4, R1, R4, R5, R6, and s are as defined in the specification.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.