Diacylglycerol acyltransferase 2 inhibitors

US9440949B2 · kind B2 · utility

Assignee

• PFIZER INC. · US

Inventors

• Shawn Cabral · Groton, US
• Kentaro Futatsugi · Sharon, US
• David Hepworth · Concord, US
• Kim Huard · Berkeley, US
• Daniel Wei-Shung Kung · Salem, US
• Suvi Tuula Marjukka Orr · San Diego, US
• Kun Song · Beijing, CN

Key dates

• Filing date: Mar 10, 2015
• Grant date: Sep 13, 2016
• Expiry date: Mar 10, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.