Compositions, formulations and methods for treating ocular diseases
US9440963B2 · kind B2 · utility
30Cited by
30References
60Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 14, 2014 |
| Grant date | Sep 13, 2016 |
| Priority date | — |
| Expiry date | May 18, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/54
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.