Animal models and therapeutic molecules
US9445581B2 · kind B2 · utility
46Cited by
21References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 28, 2012 |
| Grant date | Sep 20, 2016 |
| Priority date | — |
| Expiry date | Mar 28, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2015/8518
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanized antibodies; compositions comprising the disclosed antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in the disclosed methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.