Patent · US Active

Integrated microfluidic device for single oocyte trapping

US9445840B2 · kind B2 · utility

5Cited by

2References

41Claims

0Family size

Assignees

TSINGHUA UNIVERSITY · CN
CAPITALBIO CORPORATION · CN

Inventors

Chao Han · Columbus, US
Guoliang Huang · Beijing, CN
Jing Cheng · Beijing, CN

Key dates

Filing date	Jun 17, 2011
Grant date	Sep 20, 2016
Priority date	—
Expiry date	Jan 28, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12M47/04
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

An integrated microfluidic device and its usage are provided. The microfluidic device comprises an upper layer (1) and a lower layer (2), wherein the lower layer (2) is bound to the upper layer (1). The upper layer (1) comprises a micro-channel (3) and the lower layer (2) comprises a micro-well (7) array. The micro-channel (3) is in fluidic connection with the micro-well (7) array, and the height of the micro-channel (3) is greater than the diameter of the oocyte (4) flowing through the micro-channel (3). The integrated microfluidic device has many advantages including low cost, high integration, and convenient operation, and has application prospects in reproductive medicine and the research of fertilization and embryo early development.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.