Compositions and methods for neovascularization
US9446031B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jan 16, 2013 |
| Grant date | Sep 20, 2016 |
| Priority date | — |
| Expiry date | Jun 11, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/998
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention is directed to a method of inducing angiogenesis at a site in an individual in need thereof comprising administering locally to the site an effective amount of one or more agents that induce hypoxia induced factor 1α (HIF-1α). In another aspect, the invention is directed to a method of inducing angiogenesis at a site in an individual in need thereof comprising administering locally to the site an effective amount of one or more agents that induce hypoxia induced factor 1α (HIF-1α) and one or more lysophospholipids. In addition, the invention is directed to methods of generating prevascularized tissue, methods of generating a vascular network in a device and compositions thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.