Patent · US Active

PRMT1 inhibitors and uses thereof

US9447079B2 · kind B2 · utility

37Cited by
24References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 14, 2014
Grant dateSep 20, 2016
Priority date
Expiry dateMar 14, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D405/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Described herein are compounds of Formula (I-a) and (I-b), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT1 activity. Methods of using the compounds for treating PRMT1-mediated disorders are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.