Patent · US Active

Substituted pyrazolo[1,5-a]pyrimidines as bruton's tyrosine kinase modulators

US9447106B2 · kind B2 · utility

24Cited by
4References
23Claims
0Family size

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Inventors

Key dates

Filing dateMay 27, 2015
Grant dateSep 20, 2016
Priority date
Expiry dateMay 27, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D519/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention is substituted 4,5-dihydro- and 4,5,6,7-tetrahydro-pyrazolo[1,5-α]pyrimidine compounds of formula (I),and salts thereof, compositions thereof, and methods of use therefor, such as inhibiting protein kinase, including Bruton's tyrosine kinase (Btk), and for treating disorders mediated thereby.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.