Variant activin IIB receptor
US9447165B2 · kind B2 · utility
8Cited by
61References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 11, 2014 |
| Grant date | Sep 20, 2016 |
| Priority date | — |
| Expiry date | Mar 11, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides variant activin IIB soluble receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the variant polypeptides and proteins. Compositions and methods for treating muscle-wasting and other diseases and disorders are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.