Use of an anti-CD200 antibody for prolonging the survival of allografts
US9447187B2 · kind B2 · utility
3Cited by
21References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 3, 2012 |
| Grant date | Sep 20, 2016 |
| Priority date | — |
| Expiry date | Sep 8, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/56
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides methods useful for prolonging the survival of an allograft organ in a recipient mammal. The methods include administration of an anti-CD200 antibody or a CD200-binding fragment of the antibody. The disclosure also provides biomarkers, a change in one or more of which indicates that an anti-CD200 antibody has produced a desired immunomodulatory effect in a mammal. Also featured are pharmaceutical compositions, kits, and solutions that contain at least one anti-CD200 antibody and are useful in the methods described herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.