Generation of induced pluripotent stem cells from small volumes of peripheral blood
US9447382B2 · kind B2 · utility
18Cited by
7References
14Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Feb 12, 2014 |
| Grant date | Sep 20, 2016 |
| Priority date | — |
| Expiry date | Mar 28, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods and compositions relating to the production of induced pluripotent stem cells (iPS cells) are disclosed. For example, induced pluripotent stem cells may be generated from peripheral blood cells, such as human blood progenitor cells, using episomal reprogramming and feeder-free or xeno-free conditions. In certain embodiments, the invention provides novel methods for improving overall reprogramming efficiency with low number of blood progenitor cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.