Systems and methods for control of illumination or radiation collection for blood glucose and other analyte detection and measurement using collision computing

US9448165B2 · kind B2 · utility

Assignee

• Zyomed Corp. · US

Inventors

• Sandeep Gulati · Tustin, US
• Timothy L. Ruchti · Gurnee, US
• John L. Smith · Los Altos, US
• William P. Van Antwerp · Valencia, US

Key dates

• Filing date: Mar 25, 2016
• Grant date: Sep 20, 2016
• Expiry date: Mar 25, 2036

Classification

• Technology area (CPC G): Physics
• CPC primary: G16H50/70
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

In a noninvasive system for detection/measurement of glucose and other analytes in a medium such as tissue, illumination is directed to the medium and corresponding radiation from the medium is collected. Spectral energy changes associated with fragment(s)/feature(s) obtained from the collected radiation are determined using collision computing. Such spectral energy changes generally represent analyte concentration. The collection of radiation and/or illumination is controlled either to target a particular volume of the medium or such that the spectral energy changes become directionally monotonic with respect to analyte concentration, or both. The collection parameters include: duration of collection, location and/or a size of a collection spot on the medium surface, and angle of a collector relative to the medium surface. The illuminated and/or collection spots may be treated to improve accuracy of analyte measurement.