Bourvadin derivatives and therapeutic uses thereof
US9452215B2 · kind B2 · utility
1Cited by
12References
28Claims
0Family size
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Key dates
| Filing date | Feb 21, 2013 |
| Grant date | Sep 27, 2016 |
| Priority date | — |
| Expiry date | Feb 21, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed at bouvardin analogs arid related compounds for the treatment of disorders including cancer. Provided herein are bouvardin analogs and related compounds, pharmaceutical compositions and kits comprising at least one bouvardin analog or related compound, and methods for treating disorders including cancer. In some aspects the compounds inhibit translation elongation at the ribosome. The compounds are used in combination with radiation therapy or with known chemotherapeutic compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.