Coupling compounds of NSAID anti-inflammatory and analgesic drugs and EGFR kinase inhibitors, synthesis methods and applications thereof
US9452220B2 · kind B2 · utility
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Key dates
| Filing date | Dec 23, 2014 |
| Grant date | Sep 27, 2016 |
| Priority date | — |
| Expiry date | Dec 23, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses coupling compounds of a structure as shown in Formula I, II or III formed by connecting NSAID anti-inflammatory and analgesic drugs and EGFR inhibitors by ester bonds or pharmaceutically acceptable salts or stereoisomers thereof or prodrug molecules thereof:
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.