Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted) picolinates

US9452984B2 · kind B2 · utility

Assignee

• DOW AGROSCIENCES LLC · US

Inventors

• Kim E. Arndt · Carmel, US
• James M. Renga · Midland, US
• Yuanming Zhu · Carmel, US
• Gregory T. Whiteker · Carmel, US
• Christian T. Lowe · Westfield, US

Key dates

• Filing date: Jun 9, 2015
• Grant date: Sep 27, 2016
• Expiry date: Jun 9, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/81
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

4-Amino-3-chloro-5-fluoro-6-(substituted)picolinates are conveniently prepared from 3,4,5,6-tetrachloropicolinonitrile by a series of steps involving fluorine exchange, amination, halogen exchange and hydrolysis, esterification and transition metal assisted coupling.