Patent · US Active

Process for the purification of a growth factor protein

US9453045B2 · kind B2 · utility

3Cited by

3References

18Claims

0Family size

Assignee

OCTAPHARMA AG · CH

Inventors

Gustav Gilljam · Älta, SE
Stefan Winge · Kramfors, SE
Maya Tiemeyer · Ladenburg, DE

Key dates

Filing date	Mar 30, 2011
Grant date	Sep 27, 2016
Priority date	—
Expiry date	Mar 30, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K14/575
WIPO fieldChemical engineering
WIPO sectorChemistry

Abstract

A process of purifying the Growth Factor Protein G-CSF (Granulocyte Colony Stimulating Factor) in a purification sequence employing chromatography, comprising binding the G-CSF to Capto MMC™, which is a multimodal resin that comprises a negatively charged 2-(benzoylamino) butanoic acid ligand, at a pH from 4 to 6.2; and eluting the G-CSF at a pH greater than 6.3.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.