Glucose dependent insulinotropic polypeptide analogs, pharmaceutical compositions and use thereof
US9453062B2 · kind B2 · utility
2Cited by
0References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 8, 2012 |
| Grant date | Sep 27, 2016 |
| Priority date | — |
| Expiry date | Jun 8, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a GIP analog, which is derived from GIP (1-29, SEQ ID NO: 1), has both GLP-1 agonist activity and GIPR stimulation activity, and comprises an amino acid sequence represented by the following formula I: Tyr-A2-A3-Gly-Thr-Phe-A7-Ser-Asp-Tyr-Ser-A12-A13-A14-A15-Lys-A17-A18-A19-A20-A21-A22-A23-A24-Trp-Leu- A27-A28-A29-Y. The present invention also provides a pharmaceutical composition comprising the GIP analog and use thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.