Patent · US Active

Dual receptor antagonistic antigen-binding proteins and uses thereof

US9453080B2 · kind B2 · utility

3Cited by

0References

21Claims

0Family size

Assignee

AMGEN INC. · US

Inventors

Huiquan Han · Thousand Oaks, US
Xiaolan Zhou · Newbury Park, US
Qing Chen · 流花街道, CN
Mei-Mei Tsai · Taipei, TW

Key dates

Filing date	Jun 11, 2013
Grant date	Sep 27, 2016
Priority date	—
Expiry date	Jun 11, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This disclosure relates to antagonistic dual receptor antigen-binding proteins, e.g. antibodies and methods of using the dual receptor antibodies for treatment of pathological diseases. The dual receptor antibodies may comprise an antibody to ActRII receptors and may be used to treat pathological condition. The pathological conditions can comprise muscle wasting diseases or any disease that requires stimulation of muscle growth.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.