Organosulfur compounds for the prevention and treatment of neurodegenerative diseases
US9456999B2 · kind B2 · utility
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4Claims
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Key dates
| Filing date | Dec 5, 2011 |
| Grant date | Oct 4, 2016 |
| Priority date | — |
| Expiry date | Jul 5, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/28
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
S-allylmercapto-N-acetylcysteine and related compounds are disclosed which can be administered in order to provide protection from the formation of aldehyde-protein adducts, protein carbonylation, protein aggregation, and the resulting neuroinflammation. Various neurodegenerative diseases which are suitable for treatment using these compounds include Alzheimer's disease, senile dementia, Parkinson's disease, multiple sclerosis, Lewy body disease, peripheral neuropathy, spinal cord injury, stroke and cerebral ischemia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.