Chaperonin 10-induced immunomodulation

US9457062B2 · kind B2 · utility

Assignee

• CBIO LIMITED · AU

Inventors

• Barbara Jane Johnson · Calle de la Era, AU
• Caroline Amanda Dobbin · Brisbane, AU
• Dean Jason Naylor · Forsayth, AU
• Linda Allison Ward · Forsayth, AU
• Inge E A Flesch · Belconnen, AU
• Christopher Bruce Howard · Calle de la Era, AU

Key dates

• Filing date: Jul 11, 2006
• Grant date: Oct 4, 2016
• Expiry date: May 23, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K16/18
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to methods for modulating Toll-like receptor signalling in a subject, or in at least one cell, tissue or organ thereof, methods for treating or preventing a disease or condition in a subject, methods for modulating the production and/or secretion of one or more immunomodulators in a subject, or at least one cell, tissue or organ thereof, wherein said methods involve the administration of chaperonin 10, and wherein the chaperonin 10 associates with a Toll-like receptor in an activation cluster. Also contemplated are associated compositions and uses thereof.