Implantable drug delivery device with bladder retention feature
US9457176B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 6, 2011 |
| Grant date | Oct 4, 2016 |
| Priority date | — |
| Expiry date | Oct 6, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2210/1085
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Implantable devices and methods for controlled drug delivery are provided. The device includes a device structure deformable between a retention shape and a low profile shape for deployment in the bladder of a patient and has a drug reservoir lumen in which a drug formulation is housed. The device also includes a buoyancy retention portion, which includes a volume of entrapped air or a gas-generating or effervescent powder which will generate a volume of entrapped air following contact with urine in the bladder. The buoyancy retention portion may include a water permeable and/or biodegradable wall, which can release the entrapped air following drug release, to cause the device to sink into the bladder neck to facilitate device expulsion without the need for a device retrieval medical procedure.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.