Pyrrolopyridazines as potassium ion channel inhibitors

US9458164B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Heather Finlay · Skillman, US
• Ashok Kumar Adisechan · Puducherry, IN
• Prashantha Gunaga · Savanuru, IN
• John Lloyd · Yardley, US
• Srinivasu Pothukanuri · Bengaluru, IN

Key dates

• Filing date: Mar 10, 2014
• Grant date: Oct 4, 2016
• Expiry date: Mar 10, 2034

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P37/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A compound of formula (I) wherein A, R1, R3, and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.