Methods and compositions for the rapid production of retinal pigmented epithelial cells from pluripotent cells
US9458428B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Jun 5, 2013 |
| Grant date | Oct 4, 2016 |
| Priority date | — |
| Expiry date | Jun 12, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2506/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to the field of cell culture, specifically, the derivation of retinal pigmented epithelial cells from pluripotent cells. The invention comprises the use of various cell culture medium supplements, medium formulations, and methods of using such medium supplements and formulations, in order to effect the rapid differentiation of pluripotent cells into retinal pigmented epithelial cells with very high yields. The invention further includes cell culture media formulations for the efficient maintenance, propagation, and maturation of cultured retinal pigmented epithelial cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.