Patent · US Active

Auristatin drug linker conjugates

US9463252B2 · kind B2 · utility

5Cited by

32References

43Claims

0Family size

Assignee

SEATTLE GENETICS, INC. · US

Inventors

Peter D. Senter · Seattle, US
Svetlana O. Doronina · Snohomish, US
Timothy Bovee · Seattle, US

Key dates

Filing date	Oct 23, 2013
Grant date	Oct 11, 2016
Priority date	—
Expiry date	Apr 13, 2034

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Drug Linker compounds and Drug Linker Ligand conjugates are provided that have auristatins linked via the C-terminus. The conjugates show efficacy without the need for a self-immolative group to release the drug.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.