Patent · US Active

Nanoparticles of cerium oxide targeted to an amyloid beta antigen of alzheimer's disease and associated methods

US9463253B2 · kind B2 · utility

0Cited by

43References

5Claims

0Family size

Assignees

University of Central Florida Research Foundation · US
University of L'Aquila · IT

Inventors

Sudipta Seal · Oviedo, US
Soumen Das · Survanagiri, IN
Annamaria Cimini · L'Aquila, IT
Barbara D'Angelo · L'Aquila, IT

Key dates

Filing date	Nov 3, 2014
Grant date	Oct 11, 2016
Priority date	—
Expiry date	Nov 3, 2034

Classification

Technology area (CPC B)Performing Operations; Transporting
CPC primaryB82Y5/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed is a composition immunologically targeted to Alzheimer's disease (AD), the composition containing amine functionalized nanoparticles of Cerium oxide coated with polyethylene glycol and bearing an antibody specific for an amyloid-beta antigen associated with AD. The invention also includes a medication manufactured with the targeted nanoceria particles and methods of treatment by administering the targeted nanoceria particles to patients in need thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.