Cell adhesive material for biological tissue
US9463262B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Nov 1, 2011 |
| Grant date | Oct 11, 2016 |
| Priority date | — |
| Expiry date | May 9, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2420/02
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
An object of the present invention is to provide a cell-adhesive material for biological tissues, in which the surface of a material for biological tissues (particularly metallic material) is modified strongly with a large amount of a cell-adhesive artificial peptide (P) that retains a biological activity.The present invention provides a cell-adhesive material for biological tissues including a cell-adhesive artificial peptide (P) and a material for biological tissues, wherein the cell-adhesive artificial peptide (P) is immobilized on the surface of the material for biological tissues through an electrochemical reaction. The cell-adhesive artificial peptide (P) is preferably a peptide (P1) that is synthesized by a genetic recombinant microorganism and has at least one cell-adhesive minimal amino acid sequence (X) in one molecule. The number of the cell-adhesive minimal amino acid sequences (X) in one molecule of the polypeptide (P1) is preferably 3 to 50.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.