Patent · US Active

Method of preparation of stereospecific quinone derivatives

US9464021B2 · kind B2 · utility

2Cited by

3References

2Claims

0Family size

Inventors

Dilip S. Mehta · Mumbai, IN
Priya Mohan · Lubbock, US
Mayank Shastri · Vadodara, IN
Ted W. Reid · Lubbock, US

Key dates

Filing date	Oct 31, 2014
Grant date	Oct 11, 2016
Priority date	—
Expiry date	Oct 31, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D339/08
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The description provides processes for the regio and stereospecific synthesis of polyprenylatedquinone derivatives, such as Vitamin K1, K2 and Ubiquinone, exploiting dithioacetals, especially 1,3-dithiane, mediated Umpolung chemistry which works along a new concept “Inhibiting resonance delocalization (IRD)” to overcome isomerization generated due to delocalization of allyliccarbanion on the π-electron cloud of an allylic systems by the conventional synthesis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.